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Notably, L2HG-induced ferroptosis occurs independently of impaired cystine uptake, transsulfuration pathway activity, or increased GPX4-mediated GSH utilization, revealing a non-canonical ferroptosis mechanism driven by enhanced GSH catabolism

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It is one of the most commonly used intravenous solutions in healthcare settings due to its compatibility with the human body.Key Characteristics Composition: Consists of 0.9% sodium chloride, with no added bacteriostatic agents