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Description
Interestingly, B cell receptor (BCR) also has an ITAM motif which, upon phosphorylation, recruits and activates the Src family and Syk protein tyrosine kinases (PTKs) and promotes B cell proliferation and differentiation

PMID: 52 D'AlessandroANemkovTSunKLiuHSongAMonteAet al

F.LangstonJ

119 LaingJ

We need a more logical, common sense approach to TRT

That may be a rational design for local GI exposure , where systemic bioavailability may not even be the primary objective
