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Its most well-characterized mechanism involves stimulating collagen and glycosaminoglycan synthesis in skin fibroblasts, which underlies its effects on skin elasticity, firmness, and wound repair

39 A three-dose inhibition study demonstrated that yuanhuadine also reduced about 50% of the NNMT activity at 0.5 M in a biochemical assay

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30 Instead, off-target proteins like glutathione S -transferase omega-1, heme oxygenase 2, and thioredoxin domain containing 17 protein were identified
