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[DOI] [PubMed] [Google Scholar] 89.Bergmann C

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High levels of tumor GST and GT expression were employed to selectively target tumor with GST- or GT-activated drugs

The level of NAD + decreases with aging and the cumulative effects of oxidative stress ratios of NADP + and NADPH gradually shifts to higher NADP + relative to NADPH

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For example, curcumin is notoriously poorly bioavailable: in animal studies, only nanogramlevel concentrations of curcumin appear in plasma after oral dosing, and in humans even doses as high as 8 g orally can result in undetectable or extremely low plasma levels [36]