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To further validate cathepsin Bs specific role, we also utilized AAV-mediated overexpression of cathepsin B and its inhibitor cystatin A, which supports our findings

These include neurodegenerative disorders, increased cancer incidence in geriatric populations, diminished efficacy of cancer immunotherapies, and heightened susceptibility to infectious and cardiovascular diseases
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Since Vitamin C is water-soluble, any that gets left behind in either the small intestine or the bloodstream will be passed as waste in one of two ways depending on where it is abandoned

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doi: 10.1038/s41582-020-0312-z
