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.,SilversteinMN,PetittRM,SolbergJrLA,FlemingJS,KnightRCSchacterLPAnagrelide: A new drug for treating thrombocytosis.1988;318:12921294

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Moreover, CLA led to a decreased intestinal absorption of glucose and lipids, contributing to lower blood glucose and improved lipid profiles through the downregulation of the expression of glucose and lipid transporters GLUT2, GLUT5, and SLC5A1 and D36, ABCA1, and NPC1L1, respectively [203]

Additionally, IRE1 engages NF-B by interacting with TRAF2, which in turn upregulates the production of multiple cytokines and chemokines, facilitating cell apoptosis (79)

Among the DUBs, ubiquitin-specific protease 13 (USP13) is overexpressed in multiple cancers and is associated with tumorigenesis and poor prognosis