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[23] prescribed the joint intake of CHO with supplementation

Rebouche CJ, Seim H: Carnitine metabolism and its regulation in microorganisms and mammals

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Instead, carnitine assists the transport and metabolism of fatty acids into mitochondria, and in so doing, carnitine maintains a balance between free and esterified CoA, as an excess of acyl-CoA intermediates is potentially toxic to cells

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In contrast, when the concentration of carnitine in the plasma increases and the filtration load of carnitine increases, the kidney rapidly increases the rate of carnitine excretion and reduces its reabsorption efficiency to prevent the excessive accumulation of carnitine in the body