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Therapeutic effects of an inhibitor of thioredoxin reductase on liver fibrosis by inhibiting the transforming growth factor-1/Smads pathway

(320) suggested that both free and encapsulated curcumin can indirectly enhance the activity of antioxidant enzymes such as glutathione reductase, SOD, and CAT (320)

More patients had improved fibrosis and reduced fibrosis scores, but these changes were not significant

2.2 Transcriptional plasticity and gene regulatory networks Reversible DTP formation is closely associated with transcriptional rewiring, enabling cells to adapt to therapeutic stress temporarily (Fu and Chen, 2022)