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The signs and symptoms of Wilsons disease vary widely, depending on which organ is affected

Dimski DS, Buffington CA, Johnson SE, et al

Bioinformatics 29:1521 Encarnacin-Rosado J, Sohn ASW, Biancur DE, Lin EY, Osorio-Vasquez V, Rodrick T, Gonzlez-Baerga D, Zhao E, Yokoyama Y, Simeone DM et al (2024) Targeting pancreatic cancer metabolic dependencies through glutamine antagonism

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The authors reported in Hmox1 -deficient mice that lack of HO-1 expression in the damaged lung regions is positively related to an enhanced ROS and RNS production by neutrophils and macrophages, as well as with increased susceptibility to Mtb infections (224)