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Uric acid and gamma-glutamyl transferase activity are associated with left ventricular remodeling indices in patients with chronic heart failure

The truncation dramatically reduces binding to IGF binding proteins (IGFBPs), increases receptor affinity, and shortens half-lifecreating a potent, rapidly-acting growth factor with predominantly local rather than systemic effects when administered

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doi: 10.1074/jbc.M002997200

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