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With persistent hypoxia, HIF-1 remains activated and drives abnormal expression of downstream genes, including heme oxygenase-1 ( H O -1 ) (Zhai et al., 2023)

By 2050, there could be a significant rise in the number of AD patients ( 65 years) in America, from 5.8 million to 13.8 million [7]

Tau is subjected to a large numbers of PTMs at multiple sites and in terms of PTMs of Tau, phosphorylation is well-studied and found to have a definitive role in disease progression
K.StandishL

Allergology International

Carreau A-M, Baillargeon J-P
