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Glutathione is an important endogenous substance

Potential health benefits of milk thistle Varying degrees of research indicate that milk thistle may offer a fairly broad range of health benefits, principally owing to its radical-scavenging activity

[DOI] [PMC free article] [PubMed] [Google Scholar] 563.Illingworth N., Boddy A., Daly A., Veal G

It was found that reducing Mfrn1/2 in mitochondria reduced the mitochondrial iron content, oxygen consumption rate, and ATP level in fat cells, which lead to a reduction in lipogenic gene expression and lipid synthesis during lipogenic differentiation [51]
