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Adane and colleagues reported the presence of NOX2, a ROS-generating enzyme that is localized to the cytoplasm, in both bulk AML cells and LSCs [82]

doi: 10.3390/biomedicines10102476

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it also evokes beneficial effects in lowering the incidence of metabolic disorders related with aging, overweight or obesity, insulin resistance, and cardiovascular disease [19]

In future, combination of this approach with 1H-MRS in the same subjects, and potentially during the same scanning session on combined PET-magnetic resonance platforms, might investigate dysfunction of synaptic versus non-synaptic GABA and glutamate in schizophrenia