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These virus-induced vesicles could damage mitochondrial membrane integrity, release mt-DNA into circulation, compromise innate immunity, and trigger an exacerbated pro-inflammatory response in COVID-19 patients 164

A majority of the included studies assessed PLC versus placebo (11 studies, 1395 participants), and one study assessed propionyl L-carnitine (PLC) versus L-carnitine (one study, 26 participants)

Results vary

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Moreover, MitoTracker Red staining intensity in HepG2 cells was significantly lower in PA-treated cells than control cells

Acetyl-L-Carnitine Study Group.Diabetes Care