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Addressing the substantial incidence of hepatic encephalopathy in cirrhosis patients warrants profound attention and contemplation for future interventions

SLC25A39 was identified as a mitochondrial GSH importer in studies uncovering its upregulation under GSH deprivation and was found to have a direct role in transporting GSH into the mitochondria 22,23

Costantini, E., DAngelo, C

Nature 566 , 538542 (2019)

The complexes are as follows: I (NADHubiquinone reductase), II (succinateubiquinone reductase), III (ubiquinolcytochrome c reductase), IV (cytochrome oxidase), and V (ATP synthase complex F o F 1 ) [20]

The gene sequences were codon optimized and synthesized by GenScript Biotech