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Cancer Cell 39 , 240256.e11 (2021)

Dong M, Vongchampa V, Gingipalli L, Cloutier J-F, Kow YW, OConnor T, et al

On one hand, HO-1 protects healthy cells from transformation into neoplastic cells by counteracting ROS-mediated carcinogenesis and, on the other hand, HO-1 protects cancer cells, enhancing their survival and their resistance to anticancer treatment [86]

The quality of identified studies followed the methods of the Cochrane Collaboration [20], and publication bias was examined using funnel plots
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