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NAD + can be generated de novo in the kynurenine pathway, where Trp is oxygenated to N-formylkynurenine by tryptophan 2,3-dioxygenase (TDO) or indoleamine 2,3-dioxygenase (IDO) 31

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The first and second main components explain 72.26% of the total variance, with the first principal component representing 56.46% and the second principal component representing 15.80% of the total variance

Effects of exogenous insulin, glucagon, and somatostatin on islet hormone secretion in the perfused chicken pancreas

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