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Unlike GLP-1 agonists such as semaglutide or tirzepatide, which work primarily through appetite suppression, AOD-9604 directly enhances fat metabolism at the cellular level through beta-3 adrenergic receptor modulation

(2001, Int J Obes) showed that chronic treatment with AOD-9604 restored repressed beta-3 AR mRNA levels in obese mice toward lean-mouse values, characterizing a chronic-treatment mechanism that complements the fragment's acute lipolytic action

Some supply 5mg/mL, others 10mg/mL, and some provide even higher concentrations

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Administration routes tested included both intravenous injection and oral formulations delivered as capsules or tablets