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Iron efflux from the brain is primarily mediated by FPN1, the only known cellular iron exporter

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This structured, mechanismbased diagnostic framework is essential for moving beyond symptomatic treatment toward personalized, pathophysiologytargeted therapeutic strategies

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Specifically, we analyzed nicotine accumulation and distribution between roots and leaves in NtGSTU10 -overexpressing tobacco plants and performed comprehensive transcriptomic and metabolomic profiling of these tissues