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FDA Zepbound Medical Review (Soccio) escalation peak at weeks 16-20 +2.8/+5.1/+4.1 bpm, change over 20 bpm in about 10% of tirz vs 3.35% placebo, Japanese 15 mg abnormal-pulse 23.3% vs 7.1%

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10.1021/jf404648u [DOI] [PubMed] [Google Scholar] Lee, J

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[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Peng C.K., Huang K.L., Wu C.P., Li M.-H., Hu Y.-T., Hsu C.-W., Tsai S.-H., Chu S.-J