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Moreover, DNA methylation dysregulation also influences the remodeling of the tumor microenvironment, metabolic adaptation, drug resistance, immune response, and cancer-related inflammation [24,25,26,27,28]
However, the precise molecular details require further experimental clarification
However, the intervertebral disc is naturally in extreme conditions such as low oxygen, low nutrition, acidic pH, and high mechanical load
W.SunM.ZhuJ
doi: 10.1093/milmed/usaf092
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