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doi:10.1111/j.1440-1819.2012.02392 28 Powers, S

490 Furthermore, Sir2 , as a mammalian homolog of SIRT1, is the downstream effector of increased Nmnat activity, which can lead to axon protection in Wallerian degeneration slow mice

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As such GGT plays an integral role in GSH homeostasis and has been traditionally regarded as a component of the cellular defense system against oxidative stress (Pompella et al., 2007)