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The extracellular matrix proteins decorin, perlecan, and biglycan have all been reported as upregulated targets

Extensive scientific evidence underscores the role of persistent inflammation in promoting neurodegenerative disorders

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It has been reported that supplementation with 200 mg/day -tocopherol increases mitogen-induced proliferation of lymphocytes and the production of interleukin-2 (IL-2), which is important for the growth and development of peripheral immune cells (de La Fuente et al

Therefore, the evidence suggests that Treg dysregulation, as reflected in altered transcriptional markers, plays a crucial role in the pathophysiology of Long COVID