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88 When lactate is used as a marker for muscle damage in patients with mitochondrial disorders, CoQ10 seems to diminish the initial rise in lactate upon exercise and increases VO 2 max, although it failed to affect the total lactate level after exercise or improve overall exercise capacity in a 2010 randomized trial

Similar content being viewed by others Background Cardiovasular disease (CVD) is the world's leading cause of death, far outstripping infectious disease mortality from malaria, HIV/AIDS, and tuberculosis [1]

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While the energy yield from this metabolic pathway differs quantitatively from astrocytic glycolysis, it significantly contributes to maintaining astrocyte metabolic homeostasis and preserving ROS-mediated signaling transduction (Morant-Ferrando et al