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Some studies report modest increases in lean mass (1-3 kg over 6 months), while others show maintenance of lean mass rather than significant gains

Author Contributions Conceptualization: S.B.A

Beyond stem cell activity, another proposed mechanism involves NAD+ replenishment

PMCID: PMC12605741

Over the course of 10 to 20 years, primary sclerosing cholangitis eventually progresses from early to late-stage liver disease, and finally, liver failure

Furthermore, given that the patients with high pre-treatment CD38 levels on MM cells have a better response to Daratumumab monotherapy, high CD38 expression on MM cells seems satisfactory to maximize the clinical efficacy such as the combination treatment of CD16F158V CD38 low NK cells and Daratumumab [120]