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We chose P90 as the time of investigation, because this is a symptomatic stage with profound CSMN loss, and it coincides to the disease stage, when patients show symptoms and TDP-43 pathology begins to occur

It was discovered that humans generate different kinds of urinary proteins, but they also accord with the same family to which alpha-2-globulin accords with that of lipocalins

M.tb infection downregulates Sirt1 expression, which is crucial for negatively modulating inflammatory responses by inhibiting the activation of TAK1, MAPK and NF-B pathways and reducing IL-6 and TNF- levels

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