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However, while BPC 157 has been marketed online and has gained attention through patents and anecdotal reports, it has not yet been approved by major medical regulatory bodies like the FDA, mainly due to the lack of human clinical trials

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Polymorphisms in various genes involved in vitamin B 12 metabolism, including the genes encoding the intrinsic factor-cobalamin receptor (60) and the holo-transcobalamin receptor (61), have been associated with increased NTD risk in some studies

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