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Anti-VEGF Treatments, Side Effects, and Efficacy Current clinically available anti-VEGF therapeutics are either derived from antibodies or are small molecule inhibitors of the tyrosine kinase receptors, including VEGFR-2 that VEGF interacts with to promote angiogenesis

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also emphasised the significance of the spray angle for optimal delivery, noting that maximum deposition occurs when the angle exceeds 60 o with a slight head tilt (Li et al., 2018)

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