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Description
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The GSH substrate binds in an extended conformation at the interface between two subunits of the trimer supported by new in vitro mutagenesis data

Increased peroxidation of lipids in AD or preclinical AD brains or cerebrospinal fluids is proven by enhanced levels of protein-conjugated 4-hydroxy-2-nonenal (HNE), F 4 , and F 2 isoprostanes (Halliwell 2006)

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In addition, interactions between T cells and macrophages can influence macrophage activation and may be associated with changes in iNOS expression and inflammatory responses in the vascular wall, thereby contributing to the immunopathogenesis of vasculitis (103)
[DOI] [PubMed] [Google Scholar] 33.Korte B.A.C., Smeets N.J.L., Colbers A., Bemt B.J.F., Gelder M.M.H.J
