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This can cause it to loosen or fall off

Patients should contact their GP if symptoms develop between scheduled injections or if they miss appointments

Two observational studies reported similar high rates of efficacy, including significant pain relief in 91% of patients after six weeks of treatment accompanied by decreases in frequency and increases in voided volumes 144 and after an average one year of treatment, 87% of patients reporting that they were pain-free with similar improvements in voiding parameters

The synthesis was structured according to the Synthesis Without Meta-analysis (SWiM) framework ( 3 Results The study selection process followed a systematic approach using predefined eligibility criteria before importing references into Rayyan for screening and deduplication

doi: 10.1016/j.cortex.2014.05.003, 93 RuegseggerG

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