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Results of TRIO-14, a phase II, multicenter, randomized, placebo-controlled trial of carboplatin-paclitaxel versus carboplatin-paclitaxel-ganitumab in newly diagnosed epithelial ovarian cancer

Taken together, our results define a new synthetic lethal combination therapy that exploits the glucose addiction phenotype by mimicking glucose deprivation-induced cell death even in the presence of glucose

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