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Some may trigger immune responses at the injection site

Granulation Tissue Maturation Granulation tissue serves as the provisional matrix filling wounds before mature scar tissue forms

Clove essential oil contains several minor constituents, including 0.91% -terpineol, 0.40% D-limonene, 0.26% p-cymene, 0.21% -muurolene, 0.13% -terpinene, 0.12% geranyl acetate, 0.11% 2-nonanone, 0.11% linalool, 0.10% terpinolene, and 0.10% germacrene B (Ahamad, 2023)

Many fillers include lidocaine, a numbing agent, and a topical numbing cream applied before the procedure

Notably, low vitamin B12 status is also a risk factor for NTDs (71), further suggesting that homocysteine toxicity may be a factor in their pathogenesis

Kasznicki 2014)