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Keembiyehetty C, Love DC, Harwood KR, Gavrilova O, Comly ME, Hanover JA

Therefore, biosynthesis and metabolism of VD are under the control of VD regulatory genes (GC/ VDBP /VD-25-hydroxylase) in the liver, while the downstream actions of the active 1,25(OH) 2 VD in muscle are mediated by glucose metabolism genes ( VDR /peroxisome proliferator-activated receptor gamma coactivator 1-alpha [ PGC-1 ]/glucose transporter type 4 [ GLUT-4 ])

Zimmermann, N

Other PAMs include benzodiazepines and Z-drugs that promote sedation, anxiolysis, muscle relaxation, and anti-seizure properties

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This is why trigger point injections often succeed where other treatments have plateaued