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in particular, data from HNE cells cultured at ALI have been shown to correlate strongly with in vivo clinical responses to CFTR modulators, serving as an effective pre-clinical tool to predict patient-specific drug efficacy

Systemic anti-inflammatory effects, improved endothelial function throughout circulation, or effects on neural tissues connecting to retina (lateral geniculate nucleus, visual cortex) could indirectly benefit vision

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The cells were split at ~7090% confluency using 0.05% trypsin-EDTA for cell detachment

[DOI] [PMC free article] [PubMed] [Google Scholar] 365.Xiao J.C., Prandovszky E., Kannan G., Pletnikov M.V., Dickerson F., Severance E.G., Yolken R.H

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