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Improved mitochondrial function in brain aging and Alzheimer disease the new mechanism of action of the old metabolic enhancer piracetam

Understanding the underlying mechanisms of CIT may help to apply appropriate therapeutic drugs

Subpopulations of AgRP/NPY neurons appear to be sufficient to promote food intake and do so by redundant pathways (Betley et al

And plasma IL-2 concentrations were higher in ITP patients than in healthy individuals, but there was no significant difference in IL-4 (Wang H

For example, melatonin has been found to stimulate the -secretase cleavage of APP in cultured neuronal and non-neuronal cells [52] via upregulation of the nonamyloidogenic ADAM10 and ADAM17 proteases

Food-derived sulfur-containing amino acid ergothioneine (ERGO) is a potential dietary supplement, which exhibits various beneficial effects in experimental animals although the preventive effects of ERGO on aging and/or age-related impairments such as frailty and cognitive impairment are unclear