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Tagliabue E, Gandini S, GarcaBorrn JC, Maisonneuve P, NewtonBishop J, Polsky D, et al

5 - - - + - 72 L-carnitine 500 mg Matell 30 10 5 40 : : app 70

It is essential for the initial transport of activated long-chain fatty acids across the mitochondrial membrane via the CPT system, thus governing the substrate flux available for both -oxidation and subsequent ketogenesis

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This observation indicates that cardiomyocytes triggered self-compensation through reduced exogenous FA uptake and increased intracellular metabolism in response to excessive lipids in the cytoplasm