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The enzyme activity is also affected by multiple phosphorylation of the serine-rich region [21]

Cpz administration resulted in significant reduction in BW over time between the two strains

This protective action is critical for maintaining cellular integrity and function across various tissues and organs

Other tumors such as paraganglioma/pheochromocytoma, pituitary adenoma, and renal carcinoma have also demonstrated SDHA germline mutations [117-121]

KSS is a severe syndromic variant of CPEO that progresses to multisystemic effects due to large deletions in the mtDNA of unknown cause

TLR4-knockout mice maintained regular estrous cycling, exhibited normalized luteinizing hormone and follicle-stimulating hormone levels, and showed reduced weight gain and improved glucose tolerance compared with wild-type controls (Dominique Wiggins et al., 2023)