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Description
Per2 rhythms in the SCN show dampened amplitude and greater fragility ex vivo in aged mice, while Per1 can be epigenetically downregulated in the aged hippocampus, both changes associated with reduced robustness of circadian outputs and cognitive decline (Nakamura et al., 2015
Angewandte Chemie International Edition 2021, 60 (36), 1995719964
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[20,38] Protandim induces NRF2 nuclear translocation and subsequent transcription of the prototypical NRF2-regulated gene heme oxygenase-1 (HO-1) in human endothelial cells in vitro , [51] as well as transcription of erythrocyte SOD and catalase in vivo [38]
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Glutathione and vitamin C work together in your antioxidant defense system
