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However, insulin resistance has been reported for other mouse models with extended longevity, including Klotho transgenic mice [34], IRS1 / mice [37] and mice with a brain specific deletion of IRS2, which are long-lived when fed a high fat diet [38]

Ajees, A.A

doi: 10.1016/j.ejogrb.2014.06.008 148 FangFNiKCaiYShangJZhangXXiongC

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