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Extended Hildebrand approach: Solubility of caffeine in dioxane-water mixtures

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[DOI] [PMC free article] [PubMed] [Google Scholar] 116.Williams L.M., Berthon B.S., Stoodley I.L., Williams E.J., Wood L.G

Influence of CYP2D6*10 on the pharmacokinetics of metoprolol in healthy Korean volunteers

As an enzymatic cofactor in the synthesis of monoamine neurotransmitters, including serotonin and dopamine, reduced BH4 levels contribute to decreased 5-Hydroxytryptamine (5-HT) and dopamine (DA) levels, which induces depressive-like behaviors (Nasser et al., 2014