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Their entire personality and behavior may change drastically

617 The metabolite -KG from glutamine breakdown has been identified as a crucial player involved in epigenetic reshaping mediated by glutamine breakdown, acting as a co-factor for peroxidases and regulating histone and DNA methylation levels in glutamine breakdown-mediated epigenetic reshaping

As research continues to uncover the complex interplay between NSCs and the epileptic brain, further optimization of NSC-based therapies, including the manipulation of their secretory profiles and differentiation pathways, holds great promise for effectively treating epilepsy and improving the quality of life for patients suffering from this debilitating disorder