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Acknowledgments The authors acknowledge IntelliMed Healthcare Solutions, Mumbai, for data analysis and medical writing support

These effects are most likely due to IGF-1-induced increased calcitriol synthesis, resulting in enhanced intestinal and renal calcium absorption ( vide supra )

Synthetic GHK-Cu used in laboratory studies offers consistent peptide identity and metal coordination, supporting reproducibility across experimental assays

IGF-1 signalling regulates Mitochondria dynamics and turnover through a conserved GSK-3beta-Nrf2-BNIP3 pathway