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Prevalence and Predictors of Premature Graying of Hair Before the Age of 30: A Cross-Sectional Study in Saudi Arabia

These effects were accompanied by downregulated expression of uPA as well as uPA mRNA
doi: 10.1007/BF01504608

We note that thrombin is a well known activator of pro-inflammatory proteinase activated receptor 1 (PAR1) signalling, so some of the effects of thrombin inhibition may be mediated through reduced PAR1 activity 234

What role does copper play

Insufficient synthesis of ATP can also cause protein and lipid degradation
