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However, GLP-1 is rapidly degraded by the enzyme dipeptidyl peptidase IV (DPP IV), making it unattractive as a therapeutic agent

Im not sure where you are getting your information, but good topic

In a phase 2 trial, once-weekly cagrilintide produced dose-dependent weight reductions in people with overweight or obesity, which is what moved the amylin pathway into serious combination development ( Lau et al., Lancet 2021 )
Hepatol 58:73642 [DOI] [PubMed] [Google Scholar] 111.Dewidar B, Meyer C, Dooley S, Meindl-Beinker AN

Recent studies have investigated the use of in ovo supplementation of bioactive substances to mitigate the negative impacts of heat stress in poultry, especially in broilers due to their fast-growing body and increased metabolic rate (156, 180183)
