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Lipid droplet-associated mitochondria exhibit increased fatty acid oxidation, as indicated by elevated levels of phosphorylated ACC2 (pACC2), Mitofusin 2 protein (MFN2) and CPT1 activity, but are damaged by fatty acid oxidation in an NAFLD rat model [56]

Rapid development of colitis in NSAID-treated IL-10-deficient mice
We define reparative fibrosis as the formation of an organized fibrotic tissue that helps to mechanically stabilize the degenerating tissue defect

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Mitochondrial signal transduction mechanisms are complex and diverse, covering a wide range of signal recognition and processing from the cell to the external environment, such as oxidative stress, mtROS signaling pathway, Ca 2+ signaling, mitochondrial genome signaling, thermal signal transduction and inflammatory signaling [3, 39, 40]
