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NADH generated from the tricarboxylic acid cycle delivers its electron to the N module

This review did not comprehensively address the variability in the individual responses to carnitine supplementation, such as genetic factors or differences in gut microbiota composition, which may significantly influence TMAO production and the associated risks

While the body can naturally produce L-carnitine through this pathway, it can also be supplemented through external sources

Aberrant activation of the coagulation cascade, abnormal excess of TF on the endothelial wall and high plasma levels of different coagulation factors drive increased thrombin and fibrin production leading to further inflammation and risk of VOC (Sundd et al., 2019)