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The precise cause of most thyroid nodules remains unknown
Researchers are thus focusing on developing inhibitors that target drug-resistant isoforms, enhancing the effectiveness of existing chemotherapeutics

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Undoubtedly, further studies are still warranted to analyse the relationship between mitochondrial dysfunction and RA, thus providing new ideas and a solid foundation for the development of more precise, efficient, and safe mitochondria-targeted therapeutic strategies for RA

Increased FOXO4 expression correlates with enhanced proteasomal activity, leading to a reduction in the accumulation of damaged proteins, particularly in cardiovascular tissue

Supplementary Table 6), and 0.5 M reverse primer (CRISPRi_PCR_2_R
