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Systemic symptoms such as fatigue, nausea, and mental confusion arise from the accumulation of uremic toxins
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It is also a key nutrient required for the body to make serotonin, which naturally enhances mood
How widespread is the copper-chelation independent protein inhibition and could this be a reason for oligodendrocyte death
6 8 23 24 25 However, in many people, neurological and neuropsychological or cognitive symptoms (box 1, fig 1) are the main presenting symptoms
