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Three general ways exist for dysbiosis to contribute to the onset of chronic disease: (1) gain of function dysbiosis, where pathogens and their functions are acquired or opportunistically overgrown

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71 Considerable differences in the uptake, tissue distribution and excretion of 1,3-dinitrobenzene were observed between GF and conventional rats 71 but it cannot be concluded whether these differences are due to direct metabolism by GI bacteria or to physiological differences such as variations in the absorptive properties of the gut wall that are altered in GF animals

Atoms are represented as spheres with conventional color coding: hydrogen (white), carbon (grey), oxygen (red), nitrogen (blue), sulfur (yellow)

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