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Ethics statement The animal studies were approved by Institutional Animal Care and Use Committee Guidelines of Qinghai University

Hydroxylation of HIF-1 by FIH1 prevents its interaction with transcriptional co-activators CBP and histone acetyltransferase p300, thereby inhibiting HIF-mediated transcription [194, 195]

doi: 10.1016/S0098-8472(01)00082-X 78 StreeterJ

With its ability to recognise and selectively eliminate senescent cells without damaging the surrounding tissue, FOXO4-DRI is among the molecular tools shaping a new generation of therapeutic approaches focused on anti-aging and regeneration

A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer

These results demonstrated that in early stages of infection coronatine may play a critical role by suppressing activation of defense-related genes including GSTs (Mittal and Davis, 1995)